9007-81-2 | Complete Freund's Adjuvant

Chemical type

• Emulsified mixture (contains heat-killed mycobacteria in mineral oil)

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• Emulsion-based immunological adjuvant

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Key properties

• Potent immunostimulant enhancing antigen presentation
• Emulsified with PLP139-151 for subcutaneous immunization
• Promotes strong T-cell and B-cell responses leading to autoimmunity
• Contributes to EAE induction by amplifying inflammation

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• Contains incomplete Freund's adjuvant (IFA) and heat-inactivated Mycobacterium tuberculosis (MTB), activates immune system, disrupts blood-brain barrier, enhances antigen presentation

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• Adjuvant in EAE immunization protocol
• Tool for inducing robust immune responses in animal models
• Facilitates study of autoimmune encephalomyelitis mimicking MS

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• Emulsifier for antigens like MOG35-55 to induce EAE in multiple sclerosis models, promotes systemic inflammation and autoimmunity

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Classification by use

• Chemicals used as immunological adjuvants
• Chemicals used in disease model induction
• Chemicals used in vaccine/emulsion formulations

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• Adjuvants in vaccine and disease model induction
• Immunostimulants in preclinical research

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A trustworthy factory and manufacturer

1. [Cite:1] Mitogen-activated protein kinase inhibitor PD98059 improves neuroimmune dysfunction in experimental autoimmune encephalomyelitis in SJL/J mice through the inhibition of nuclear factor-kappa B signaling in B cells, Brain Research Bulletin, Volume 194, March 2023, Pages 45-53
2. [Cite:2] EAE models of neuropathic pain in multiple sclerosis do not require pertussis toxin, Brain Research, Volume 1875, 15 March 2026, 150162