Alginic Acid, Calcium Salt
CAS No.: 9005-35-0
- Molecular Formula: (C₆H₇Ca₁/₂O₆)ₙ
- Molecular Weight: - g/mol
Chemical type
- Polysaccharide derivative cross-linked with calcium ions
- pH-sensitive gel polymer
- Polysaccharide gel (water-insoluble alginate salt derived from sodium alginate)
Key properties
- pH-responsive swelling and degradation
- Enzyme-responsive in colonic environment
- Stable and intact in acidic gastric conditions
- Hydrates and increases porosity at neutral pH
- Impedes diffusion of oxidative species (e.g., O₂)
- Enhances thermal, photo, and oxidative stability of encapsulants
- High hygroscopicity and moisture adsorption capacity (up to 1.009 g/g in composites with additives)
- Porous structure enhanced by freeze-drying and additives like PVP
- Good adsorption kinetics, especially when combined with silica gel or expanded graphite
- Decreased pore volume and diameter with higher Ca²⁺ concentration due to excessive cross-linking
- Improved mechanical properties (e.g., compressive strength) at higher CaCl₂ concentrations
- Thermal stability suitable for building applications
- Shell in core-shell microspheres for colon-targeted release
- Protection against premature drug release in stomach
- Sustained, site-specific delivery at inflammatory sites
- Encapsulation of PO-SECs in Ca-Alg@PO-SECs system
- Blocking penetration of simulated gastric fluid
- Moisture-adsorbing matrix in hygroscopic phase change composites (HPCC)
- Regulates indoor humidity and temperature in buildings
- Integrated with PCMs to prevent leakage and enhance performance
- Applied in gypsum boards or wall materials to increase moisture buffer value (MBV) up to 9.3 g/(m²·%RH)
Classification by use
- Biocompatible polymers for gastrointestinal drug delivery
- pH-sensitive materials in controlled-release formulations
- Protective gels in natural drug carriers
- Hygroscopic materials
- Building energy efficiency materials
- Composite matrices for phase change applications
A trustworthy factory and manufacturer
- [Cite:1] Engineered Sporopollenin Exine Capsules for Colon-Targeted Delivery and Antioxidant Therapy of Calcium Alginate in Ulcerative Colitis, Antioxidants, 2026, 15(1), 116
- [Cite:2] Study on synthesis and hygrothermal performance of calcium alginate-based moisture-adsorbing phase change composite, Next Materials, Volume 10, January 2026, 101401
