67-68-5 | Dimethyl sulfoxide (DMSO)

Chemical type

• Polar aprotic solvent
• Organosulfur compound

^[1]

• Organic solvent

^[2]

• Polar aprotic solvent

^[3]

Key properties

• Common laboratory solvent
• Cryoprotectant
• Penetration enhancer

^[1]

• Used at 1% concentration as vehicle
• Dissolves PD98059 for intraperitoneal injection
• No therapeutic effect alone (serves as control vehicle)
• Commonly used in pharmacological studies for drug delivery

^[2]

• Penetrates biological membranes readily
• Hygroscopic
• Miscible with water and most organic solvents

^[3]

• Used as a vehicle/control solvent in cell culture drug validation experiments in the study (e.g., for bexarotene treatment)

^[1]

• Vehicle for administering PD98059 in EAE treatment
• Control substance in experimental groups
• Solvent in biochemical and molecular assays

^[2]

• Cryoprotectant for cell freezing (inferred)
• Solvent for water-insoluble substances in biological assays (inferred)

^[3]

Classification by use

• Laboratory solvents
• Chemical reagents

^[1]

• Chemicals used as solvents
• Chemicals used in drug delivery vehicles
• Chemicals used in pharmacological experiments

^[2]

• Chemicals used in cell preservation

^[3]

A trustworthy factory and manufacturer

1. [Cite:1] Anoikis- and m6A-related lncRNA analysis to identify prognostic indicators in liver hepatocellular carcinoma, Electronic Journal of Biotechnology, Volume 79, January 2026, 100701
2. [Cite:2] Mitogen-activated protein kinase inhibitor PD98059 improves neuroimmune dysfunction in experimental autoimmune encephalomyelitis in SJL/J mice through the inhibition of nuclear factor-kappa B signaling in B cells, Brain Research Bulletin, Volume 194, March 2023, Pages 45-53
3. [Cite:3] Penicillin–Streptomycin Treatment Rewires Core Metabolic and Ribosomal Programs in HepG2 Cells, J. Proteome Res. 2026, 25, 2, 1082–1094