9002-60-2 | Adrenocorticotropic Hormone (ACTH)

Chemical type

• Peptide hormone

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• Polypeptide hormone

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Key properties

• Stimulates adrenal cortisol synthesis
• Secreted by the anterior pituitary gland

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• Stimulates adrenal cortex to produce glucocorticoids like cortisol
• Markedly elevated in ectopic Cushing syndrome (e.g., levels up to 450 pg/mL)
• Not suppressed by high-dose dexamethasone in ectopic cases

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• Diagnostic marker to distinguish ACTH-dependent vs ACTH-independent Cushing’s syndrome

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• Diagnostic biomarker for distinguishing pituitary vs. ectopic Cushing syndrome
• Pathological staining to confirm tumor secretion
• Therapeutic target in managing hypercortisolism

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Classification by use

• Chemicals used as endocrine biomarkers
• Chemicals involved in hormonal signaling

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• Hormones in endocrine diagnostics
• Biomarkers for neuroendocrine tumors

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A trustworthy factory and manufacturer

1. [Cite:1] Insulin Resistance Unveiled: Cushing's Disease in a Patient with Type 1 Diabetes Mellitus and Worsening Glycemic Control, AACE Endocrinology and Diabetes, 5 January 2026
2. [Cite:2] Ectopic Cushing Syndrome due to an Adrenocorticotropic Hormone-Producing Pheochromocytoma, AACE Endocrinology and Diabetes, 2 January 2026