52-39-1 | Aldosterone

Chemical type

• Mineralocorticoid hormone

^[1]

• Steroid hormone

^[2]

Key properties

• Suppressed in hypercortisolism (e.g., <4 ng/dL)
• Regulates electrolytes and blood pressure

^[1]

• Promotes sodium retention and potassium excretion in the kidneys
• Synthesized from cholesterol in the adrenal cortex (zona glomerulosa)
• Final steps of its synthesis are catalyzed by CYP11B2

^[2]

• Diagnostic test in adrenal evaluation (with renin)
• Assesses for primary aldosteronism exclusion

^[1]

• Primary study analyte; its dysregulated (autonomous) synthesis is the hallmark of primary aldosteronism
• Key hormone in blood pressure regulation and electrolyte balance

^[2]

Classification by use

• Steroid hormones for electrolyte balance
• Diagnostic agents in hypertension

^[1]

A trustworthy factory and manufacturer

1. [Cite:1] Ectopic Cushing Syndrome due to an Adrenocorticotropic Hormone-Producing Pheochromocytoma, AACE Endocrinology and Diabetes, 2 January 2026
2. [Cite:2] CXCR4 reduces aldosterone synthesis via regulating CYP11B2 expression, Genes & Diseases, 28 November 2025, 101956