633-65-8 | Berberine Hydrochloride

Chemical type

• Natural alkaloid

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• Quaternary ammonium-type isoquinoline alkaloid

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Key properties

• Low solubility and stability in oral administration
• Antimicrobial activity against pathogens like E. coli, S. aureus, and C. albicans
• Anti-inflammatory effects
• Anticancer properties
• Antidiabetic effects
• Forms inclusion complexes with cyclodextrins for enhanced bioavailability

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• One of the important active components in Chinese herbal medicine
• Exhibits high peak absorption at 225-235 nm, 263-268 nm, 344-352 nm, and 427-431 nm

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• Model drug in hydrogel formulations
• Oral delivery for therapeutic effects
• Antimicrobial agent
• Anti-inflammatory treatment
• Anticancer therapy
• Antidiabetic medication

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• Used as a quantitative index component (marker) for quality control and standardization of Corydalis conspersa. It is also a key active ingredient in other medicinal plants like Coptidis rhizoma and Berberidis Radix.

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Classification by use

• Therapeutic alkaloids
• Antimicrobial drugs
• Anti-inflammatory agents
• Anticancer compounds
• Antidiabetic substances

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• Chemicals used as pharmaceutical reference standards
• Chemicals used in quality control of traditional medicine

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A trustworthy factory and manufacturer

1. Oral Administration of Berberine Hydrochloride Based on Chitosan/Carboxymethyl-β-Cyclodextrin Hydrogel, Polymers, 2024, 16(16), 2368
2. Quantitative determination of coptisine and berberine hydrochloride in Corydalis conspersa by high-performance liquid chromatography and quality evaluation, Chinese Journal of Analytical Chemistry, Volume 53, Issue 10, October 2025, 100620