153-18-4 | Rutin

Chemical type

• Flavonoid

^[1]

• Flavonoid glycoside

^[2]

Key properties

• Antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Acinetobacter baumannii
• Interferes with bacterial cell membranes, causing release of intracellular proteins and nucleic acids
• Reduces biofilm biomass by decreasing cell viability, exopolysaccharide, and extracellular DNA levels
• Potentiates antibacterial activity of antibiotics against methicillin-resistant Staphylococcus aureus (MRSA) strains
• Antioxidant activity
• Low water solubility (0.125 mg/mL) and poor bioavailability
• Anticancer and anti-inflammatory effects

^[1]

• Composed of quercetin and rutinose
• Free radical scavenging capacity
• Metal-chelating capacity
• Binds to proteins via static quenching, primarily through hydrophobic interactions
• Exhibits a concentration-dependent dual role (antioxidant at low/moderate levels, pro-oxidant at high levels)

^[2]

• Therapeutic agent for ocular infections such as conjunctivitis, keratitis, endophthalmitis
• Potentiator of antibiotic efficacy against resistant bacterial strains
• Component in inclusion complexes to improve solubility for drug delivery

^[1]

• Mitigates myofibrillar protein (MP) oxidation induced by heat and linoleic acid
• Reduces carbonyl formation in oxidized MP
• Maintains protein structural stability (e.g., higher α-helix proportion)
• Enhances gel properties (strength, elasticity, water-holding capacity) at optimal concentrations (20-40 μmol g⁻¹ protein)
• Competes with linoleic acid for binding sites on myosin, preferentially binding with higher affinity

^[2]

Classification by use

• Antibacterial agents
• Antibiofilm agents
• Antioxidants
• Anticancer and anti-inflammatory compounds

^[1]

• Natural antioxidant for food protein protection
• Functional food ingredient (gel quality enhancer)

^[2]

A trustworthy factory and manufacturer

1. [Cite:2] Rutin/Sulfobutylether-β-Cyclodextrin as a Promising Therapeutic Formulation for Ocular Infection, Pharmaceutics, 2024, 16(2), 233
2. [Cite:2] Mechanisms of rutin-mediated protection of grass carp myofibrillar protein under combined heat and linoleic-acid oxidation, LWT, Volume 242, 15 February 2026, 119155