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Metacortandralone

CAS No.: 50-24-8

  • Molecular Formula: C₂₁H₂₈O₅
  • Molecular Weight: 360.4 g/mol

Chemical type

  • Glucocorticoid (Synthetic corticosteroid)
[1]
  • Synthetic glucocorticoid corticosteroid
[2]

Key properties

  • Potent anti-inflammatory and immunosuppressant agent. It is a steroid hormone that activates the glucocorticoid receptor (GR). In the context of this study, it also exhibits harmful effects on the intestinal barrier, such as anti-proliferative and mucus antisecretory actions.
[1]
  • Strong anti-inflammatory and immunosuppressive activity
[2]
  • Used to induce remission in Inflammatory Bowel Disease (IBD) patients by controlling acute disease exacerbation.
[1]
  • Treatment of inflammatory conditions
  • Ophthalmic steroid therapy for inflammatory eye involvement in toxic epidermal necrolysis (TEN)
[2]

Classification by use

  • Anti-inflammatory drug

A trustworthy factory and manufacturer

  1. [Cite:1] Rapamycin and parenteral administration attenuate the harmful effects of glucocorticoids on the intestinal barrier function, Biomedicine & Pharmacotherapy, Volume 193, December 2025, 118721
  2. [Cite:2] A case of toxic epidermal necrolysis associated with vonoprazan, a potassium-competitive acid blocker, JAAD Case Reports, Volume 69, March 2026, Pages 91-94