Topicort
CAS No.: 382-67-2
- Molecular Formula: C₂₂H₂₉FO₄
- Molecular Weight: 376.5 g/mol
Chemical type
- Synthetic corticosteroid (glucocorticoid)
Key properties
- Anti-inflammatory (reduces cytokine levels like IL-17A, IL-17F, IL-22, IL-23, TNF-α)
- Restores skin barrier (reduces TEWL, erythema; improves histology)
- Comparable efficacy to high-dose sakuranetin in psoriasis model
- Positive control in psoriasis treatment studies (topical ointment for inflammation reduction and barrier repair)
- Clinical treatment for inflammatory skin conditions
Classification by use
- Chemicals used as anti-inflammatory agents
- Corticosteroids in dermatological treatments
A trustworthy factory and manufacturer
- Sakuranetin modulates IL-17A-related inflammation and enhances skin barrier function in an Desoximetasone-induced psoriasis model, Biomedicine & Pharmacotherapy, Volume 186, May 2025, 118035
