4235-95-4 | DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine)

Chemical type

• Phospholipid
• Component of lipid bilayers

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• Unsaturated zwitterionic phospholipid (C18:1 chains)

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• Phospholipid

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Key properties

• Used to model cell membranes in simulations
• Provides hydrophobic environment for protein studies

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• Fluid-phase model membrane lipid (unsaturated tails)
• Zwitterionic over wide pH range (pKa phosphate ~2, ammonium ~9)
• Forms stable monolayers (collapse ~43–47 mN/m depending on subphase)

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• Forms liposomes (lipid bilayers)
• Slightly negative surface charge at pH 5.5
• Biocompatible

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• Membrane model in molecular dynamics simulations
• Used to study nanoparticle–membrane interactions

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• Standard model for fluid biological membranes in Langmuir-Blodgett studies
• Assessment of biocompatibility of Ch/HA/TiO₂ composites

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• Serves as a soft, sacrificial template for assembling polypeptide multilayers. The liposome's cavity is used to encapsulate molecules (HPTS, calcein) during fabrication.

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Classification by use

• Model lipids for membrane biophysics & biocompatibility testing

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• Template material for nanoencapsulation

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A trustworthy factory and manufacturer

1. [Cite:1] Toxic Effect of Fullerene and Its Derivatives upon the Transmembrane β2-Adrenergic Receptors, Molecules, 2022, 27(14), 4562
2. [Cite:2] The effect of chitosan/TiO2/hyaluronic acid subphase on the behaviour of 1,2-dioleoyl-sn-glycero-3-phosphocholine membrane, Biomaterials Advances, Volume 138, July 2022, 212934
3. [Cite:3] Multilayer nanoarchitectonics of polypeptide capsules with size-selective permeability, Journal of Colloid and Interface Science, Volume 708, 15 April 2026, 139842