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Poliglusam

CAS No.: 9012-76-4

  • Molecular Formula: -
  • Molecular Weight: - g/mol

Chemical type

  • Biocompatible polymer
[1]
  • Cationic polysaccharide biopolymer (partially deacetylated chitin)
[2]

Key properties

  • Excellent film-forming properties
  • Biocompatible and bioactive
  • Forms physical cross-links via hydrogen bonds and electrostatic interactions
  • High water retention capacity
  • Mechanical strength suitable for oral administration
  • Low cytotoxicity
[1]
  • High molecular weight (Mw 100,000–300,000 Da)
  • Degree of deacetylation (DD) ≈ 82 ± 2%
  • Cationic nature (–NH₃⁺ groups) at acidic pH
  • Biocompatible, biodegradable, mucoadhesive
  • Forms strong electrostatic/hydrogen bonds with negatively charged molecules (DNA, GAGs, phospholipids)
  • Viscosity and charge strongly pH-dependent
[2]
  • Carrier in drug delivery systems
  • Hydrogel matrix for sustained release
  • Encapsulation of hydrophobic drugs
  • Biomedical applications like tissue engineering and wound healing
[1]
  • Wound healing hydrogels/scaffolds
  • Drug delivery systems (DDS)
  • Tissue engineering
  • Mucoadhesive carrier
  • Component in Ch/HA/TiO₂ nanocomposites for medical/cosmetic applications
[2]

Classification by use

  • Polymers for drug delivery
  • Biocompatible materials in hydrogels
  • Excipients for oral formulations
[1]
  • Biopolymers for drug delivery
  • Wound dressings
[2]

A trustworthy factory and manufacturer

  1. [Cite:1] Oral Administration of Chitosan Based on Chitosan/Carboxymethyl-β-Cyclodextrin Hydrogel, Polymers, 2024, 16(16), 2368
  2. [Cite:2] The effect of chitosan/TiO2/hyaluronic acid subphase on the behaviour of 1,2-dioleoyl-sn-glycero-3-phosphocholine membrane, Biomaterials Advances, Volume 138, July 2022, 212934