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4-Hydroxy-3-methoxycinnamic acid

CAS No.: 1135-24-6

  • Molecular Formula: C₁₀H₁₀O₄
  • Molecular Weight: 194.18 g/mol

Chemical type

  • Phenolic acid
[1]
  • Polyphenol
[2]

Key properties

  • Antioxidant with anti-inflammatory and neuroprotective effects; enhances mango's health-promoting properties.
[1]
  • Low cytotoxicity (safe for human oral epithelial cells even at high concentrations)
  • Weak antimicrobial activity (bactericidal against P. gingivalis, bacteriostatic against A. actinomycetemcomitans)
  • Quorum-sensing inhibitor
[2]
  • Naturally occurring in mango and utilized in fruit leathers for antioxidant benefits.
[1]
  • Inhibits biofilm formation of Porphyromonas gingivalis
  • Suppresses AI-2 production and AI-2 receptor activity (quorum sensing)
  • Potential application in preventing and treating periodontal diseases
[2]

Classification by use

  • Natural antioxidant in food
  • Bioactive compound for functional foods
[1]
  • Chemicals used in dental/oral healthcare
  • Antibiofilm agents
  • Quorum-sensing inhibitors
[2]

A trustworthy factory and manufacturer

  1. [Cite:1] Unlocking the impact of citric acid and sugar on the nutritional, physicochemical, microbial and sensorial attributes of mango fruit leathers, Food Chemistry: X, Volume 33, January 2026, 103478
  2. [Cite:2] Ferulic acid suppresses Porphyromonas gingivalis biofilm formation via the inhibition of autoinducer-2 production and receptor activity, Archives of Oral Biology, Volume 178, October 2025, 106365