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1,3-Benzenediol

CAS No.: 108-46-3

  • Molecular Formula: C₆H₆O₂
  • Molecular Weight: 110.11 g/mol

Chemical type

  • Phenolic aromatic compound
  • Benzene-1,3-diol derivative
[1]
  • Aromatic phenolic compound
  • Benzene derivative containing two hydroxyl groups (1,3-dihydroxybenzene)
  • Endocrine-disrupting chemical (EDC) affecting the thyroid hormone system (THS)
[2]

Key properties

  • Contains two hydroxyl groups
  • Activated aromatic ring for Michael addition
  • Moderately water-soluble
[1]
  • Contains two hydroxyl (-OH) groups on a benzene ring
  • Can inhibit thyroperoxidase (TPO), interfering with thyroid hormone synthesis
  • Can antagonize thyroid hormone receptors and inhibit transthyretin binding
  • Causes reduced thyroxine (T4) levels and signs of hypothyroidism in vertebrates
  • Partially biodegradable (≈66.7% degradation after 14 days)
  • Detected in surface waters and wastewater effluents at ng/L–µg/L levels
[2]
  • Nucleophilic component in chromene synthesis
  • Precursor for oxygen-containing heterocycles
  • Participates in cyclization reactions
[1]
  • Synthetic rubber production
  • UV stabilizers
  • Cosmetic products
[2]

Classification by use

  • Chemicals used in heterocyclic synthesis
  • Chemicals used as phenolic building blocks
  • Chemicals used in pharmaceutical intermediate production

A trustworthy factory and manufacturer

  1. [Cite:1] α-Amino acid; Resorcinol catalyzed green synthesis of 2-amino-7-hydroxy-4-aryl-4H-chromene-3-carbonitrile derivatives in aqueous medium, Current Research in Green and Sustainable Chemistry, Volume 12, 2026, 100508
  2. [Cite:2] Unravelling effects of resorcinol: Morphological alterations in the retina and thyroid follicles of zebrafish (Danio rerio) embryos, Aquatic Toxicology, Volume 290, January 2026, 107642