10326-41-7 | D-Lactate (C₃H₆O₃)

Chemical type

• Organic acid
• Monomeric precursor for Lactate-based copolymer (LAHB)

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• Chiral organic acid (α-hydroxy acid, D-enantiomer)

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Key properties

• Converted to D-LA-CoA by PCT enzymes to become a substrate for polymerization.

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• Exists as a stereoisomer of lactate
• Product of glycolysis (via methylglyoxal pathway or LdhA in bacteria)
• Can be converted into D-lactyl-CoA
• Acts as a metabolic signaling molecule
• Accumulates under anaerobic conditions

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• Feedstock for LAHB biosynthesis.

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• Drives lysine D-lactylation (post-translational modification)
• Regulates bacterial metabolism and growth
• Serves as a metabolic intermediate and signaling molecule

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A trustworthy factory and manufacturer

1. [Cite:1] Complete sequence randomness of lactate-based copolymers (LAHBs) with varied lactate monomer fractions employing a series of propionyl-CoA transferases, International Journal of Biological Macromolecules, Volume 274, Part 2, August 2024, 133055
2. [Cite:2] D-lactate Drives Lysine D-lactylation to Regulate Metabolism in Escherichia coli, JBC, 16 March 2026, 111374