75-05-8 | Acetonitrile

Chemical type

• Polar aprotic organic solvent

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• Polar aprotic organic solvent (nitrile)

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Key properties

• Permeance through PEEK membranes around 3 L m⁻² h⁻¹ bar⁻¹
• Viscosity, molar diameter, kinetic diameter, and polar solubility parameter (δ_p) influence transport mechanisms (pore flow, solution-diffusion, friction)
• Used in mixtures at 0.25 mM per solute for testing
• Promotes higher rejection of small solutes compared to DMF in denser membranes

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• Protein precipitation solvent
• High volatility
• Compatible with LC-MS analysis
• Miscible with water

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• Permeant for evaluating PEEK membrane performance in nanofiltration
• Solvent for complex mixtures of 23 solutes (APIs, aromatics, dyes) in separation tests
• Mobile phase in HPLC analysis for concentration measurements

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• Sample preparation solvent
• Protein precipitation reagent
• Mobile phase component in LC-MS

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Classification by use

• Test solvents for membrane characterization
• Solvents in pharmaceutical and chemical separations

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• Chemicals used as analytical solvents
• Chemicals used in chromatographic analysis

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A trustworthy factory and manufacturer

1. [Cite:1] Molecular fractionation with poly(ether ether ketone) hollow fibers, Advanced Membranes, Volume 7, June 2026, 100193
2. [Cite:2] Transplacental passage of ampicillin: Implications for antenatal therapy, Placenta, Volume 175, 6 March 2026, Pages 66-72