28523-86-6 | Sevoflurane (C₄H₃F₇O)

Chemical type

• Inhaled volatile anesthetic (halogenated ether)

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• Halogenated inhalation anesthetic

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Key properties

• Low blood-gas solubility for rapid induction and emergence
• Provides hypnosis and amnesia

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• Used for general anesthesia in humans and animals
• Male reproductive toxicity in rats: decreases in testicular sperm count, LH, FSH, testosterone; apoptosis of Sertoli cells and primary spermatocytes
• Oxidative stress mechanism observed at high doses (increased malondialdehyde, decreased superoxide dismutase)
• Neurological effects: affects hippocampal theta oscillations and memory in animal studies

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• Anesthesia maintenance (1-1.5% inhalation)
• Maintains BIS 40-60 and stable hemodynamics during surgery

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• General anesthesia in hospital and veterinary settings
• Research use in animal facilities

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Classification by use

• Inhaled general anesthetics

A trustworthy factory and manufacturer

1. [Cite:1] Lidocaine mitigates cognitive decline in elderly patients after video-assisted thoracoscopic surgery: A double-blind randomized controlled clinical trial, Brain Disorders, Volume 21, March 2026, 100308
2. [Cite:2] A health-based recommended occupational exposure limit for isoflurane and sevoflurane using experimental animal data based on a systematic review and dose-response analysis, Environmental Toxicology and Pharmacology, Volume 121, January 2026, 104916