446-72-0 | Genistein

Chemical type

• Isoflavone

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• Natural isoflavone
• Phytoestrogen (plant-derived estrogen-like compound)

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Key properties

• Neuroprotective effects
• Can cross the blood-brain barrier

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• Exhibits estrogen-like biological activity (binds to ERα and ERβ)
• Anti-inflammatory properties
• Antioxidant properties
• Regulates MAPK and TGF-β signaling pathways
• Modulates steroid hormone biosynthesis
• Promotes bone metabolism
• High purity used in study (≥ 98%)

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• Protection against neurodegeneration
• Therapeutic for memory impairment and Alzheimer's

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• Dietary supplement in laying hens
• Enhancer of ovarian function
• Improves follicular development
• Reduces follicular atresia
• Increases reproductive hormone levels (LH, FSH, E2, PROG)
• Improves egg production performance (HDEP, HHEP)
• Improves egg quality (eggshell thickness, strength, weight)
• Enhances bone mineral density (BMD) and bone mineral content (BMC)
• Improves bone strength
• Regulates osteogenic gene expression (RUNX2, ALP, OCN, OPG/RANKL)
• Reduces oxidative stress (↓ MDA, ↑ SOD, ↑ CAT)
• Reduces inflammatory cytokines (↓ TNF-α, ↓ IL-1β)

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Classification by use

• Chemicals used as neuroprotective agents
• Chemicals used in blood-brain barrier permeable treatments

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• Chemicals used as phytoestrogenic agents
• Chemicals used in animal nutrition

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A trustworthy factory and manufacturer

1. [Cite:1] HRMS-based profiling of metabolites, metal ions content and in-vitro cholinesterase inhibitory activities of Sonchus wightianus DC plant parts, Electronic Journal of Biotechnology, Volume 79, January 2026, 100702
2. [Cite:2] Dietary genistein supplementation enhances reproductive and bone health in late-laying hens, Poultry Science, Volume 105, Issue 5, May 2026, 106554