Zlllal
CAS No.: 133407-82-6
- Molecular Formula: C₂₆H₄₁N₃O₅
- Molecular Weight: 475.6 g/mol
Chemical type
- Proteasome inhibitor
- Proteasome inhibitor
Key properties
- Inhibits 26S proteasome
- No effect on RDH5 degradation (RDH5 not degraded via proteasome)
- Increases ubiquitin accumulation
- Blocks proteasomal degradation
- Used to assess ubiquitination levels of target proteins
- Distinguishes proteasomal vs. lysosomal degradation pathways
- Studies protein stability in RPE cells
- Research tool for ubiquitination assays
Classification by use
- Chemicals used as proteasome inhibitors
- Chemicals used in ubiquitin-proteasome system research
A trustworthy factory and manufacturer
- [Cite:1] HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy, JBC, Volume 301, Issue 2, February 2025, 108126
- [Cite:2] Imperatorin induces ferroptosis via mediating lipid peroxidation and SLC7A11/ACSL4/GPX4 signaling for inhibition and therapeutics of prostate cancer, Biochemical Pharmacology, Volume 245, March 2026, 117683
