13292-46-1 | Rifampicin

Chemical type

• Active pharmaceutical ingredient (API)
• Antibiotic (rifamycin class)

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• Antimicrobial agent (antibiotic/antiprotozoal)

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Key properties

• Molecular weight: 823 g mol⁻¹
• Van der Waals volume: 471.4 cm³ mol⁻¹
• High rejection (>90%) by PEEK membranes, stable over long-term filtration (14 days in DMF)
• Larger size enables effective separation from smaller solutes

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• Potent antimicrobial activity
• Poor stability
• Low solubility in water
• Variable bioavailability
• Effective against Staphylococcus aureus biofilms and Leishmania species

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• Component in complex solute mixtures for evaluating PEEK membrane selectivity in OSN
• Fractionation in pharmaceutical industry processes for purification and concentration

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• Treatment of bacterial infections (e.g., MRSA)
• Treatment of leishmaniasis (a parasitic disease)
• Attack on bacterial biofilms

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Classification by use

• Pharmaceuticals for tuberculosis and bacterial infections
• Solutes in membrane performance evaluation

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• Antimicrobial drugs
• Drugs for neglected tropical diseases (Leishmaniasis)

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A trustworthy factory and manufacturer

1. [1] Molecular fractionation with poly(ether ether ketone) hollow fibers, Advanced Membranes, Volume 7, June 2026, 100193
2. [2] Development and Characterization of Pharmaceutical Systems Containing Rifampicin, Pharmaceutics, 2023, 15(1), 198