87-08-1 | Penicillin V

Chemical type

• Beta-lactam antibiotic

^[1]

• Natural penicillin compound

^[2]

Key properties

• Used as reference in LC-MS/MS quantification
• Retention time: 4.04 min in chromatographic analysis
• Transitions for quantitation: 351.1 > 160.1 (16 eV) and 351.1 > 114.1 (35 eV)

^[1]

• Administered orally as a tablet.
• Produced via fermentation of Penicillium chrysogenum using phenoxyacetic acid as a precursor.
• Acid-stable, allowing for oral absorption.

^[2]

• Internal standard in cefotaxime residue analysis in shrimp tissues and plasma

^[1]

• Treatment of bacterial infections, such as community-acquired pneumonia.
• Referenced as a Single Standard Dose (SSD) of 1 million International Units (mil. IU) for oral treatment.

^[2]

Classification by use

• Analytical reagents in pharmacokinetics studies
• Chemicals for mass spectrometry calibration

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1. [Cite:1] Pharmacokinetics and Withdrawal Times of Cefotaxime in White Leg Shrimp (Litopenaeus vannamei) after Oral Administration, Fishes, 2024, 9(6), 232
2. [Cite:2] The greener prescription: Life cycle environmental impact of oral and IV penicillin treatments, Sustainable Chemistry and Pharmacy, Volume 50, April 2026, 102346