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MK-3475

CAS No.: 1374853-91-4

  • Molecular Formula: -
  • Molecular Weight: - g/mol

Chemical type

  • Immunotherapy agent (PD-1 inhibitor)
[1]
  • Monoclonal antibody
  • Immune checkpoint inhibitor
  • PD-1 receptor inhibitor
[2]

Key properties

  • Can induce exogenous cyclic ACTH-dependent Cushing syndrome
[1]
  • Blocks programmed cell death protein 1 (PD-1)
  • Enhances T-cell–mediated immune response
  • Biologic immunotherapy agent
  • Administered intravenously
[2]
  • Cancer treatment (e.g., melanoma)
  • Associated with endocrine side effects like cyclic Cushing
[1]
  • Treatment of various advanced cancers
  • Investigated in combination with olaparib for mCRPC
  • Immunotherapy for biomarker-unselected metastatic prostate cancer
[2]

Classification by use

  • Immunotherapies
  • Medications causing endocrine disorders
[1]
  • Chemicals used as immune checkpoint inhibitors
  • Chemicals used in cancer immunotherapy
  • Biologic agents used in combination cancer therapy
[2]

A trustworthy factory and manufacturer

  1. [Cite:1] Osilodrostat for Cyclic Cushing Disease, AACE Endocrinology and Diabetes, Volume 13, Issue 1, January–February 2026, Pages 17-21
  2. [Cite:2] PARP Inhibitor Olaparib and Its Combination Therapy in Metastatic Castration-resistant Prostate Cancer: A Systematic Review and Network Meta-analysis, European Urology Open Science, Volume 84, February 2026, Pages 1-12