Essential precursor for acylation, reduction, Diels-Alder synthesis, amination, and oxidation
Undergoes acylation preferentially at the 2-position due to higher electron density
Nucleophilic aromatic, reacts with electrophiles like acetic anhydride
Can undergo side reactions such as polymerization and autoxidation with homogeneous catalysts
Substrate in Friedel-Crafts acylation to produce 2-acylfuran
Raw material for synthesis of intermediates in pharmaceuticals, food additives, and aromas
Precursor for furoic acid and furoate esters
Classification by use
Chemicals used as precursors in organic synthesis
Chemicals used in pharmaceutical intermediates (e.g., for cefuroxime and HIV integrase inhibitors)
Chemicals used in food and beverage industry (e.g., fruit aromas, tobacco smoke)
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Sustainable friedel-crafts acylation of furan using nanocrystalline ZSM-5: A green catalytic approach, Chemical Engineering Journal Advances, Volume 25, March 2026, 100970