Introduces nitrogen into carbon matrix (up to 5.6% in biochar)
Promotes microporosity increase (from 19% to 54%)
Creates smaller mesopores in doped materials
Leads to formation of N states: pyridinic, graphitic, pyrrolic, and oxidized N
[1]
Does not occur naturally in foods; short half-life and not metabolized in the body (≈90% excreted in urine); combines with cyanuric acid to form insoluble yellow spherical crystals that obstruct renal tubules; induces oxidative stress and inflammation via NF-κB/COX-2 and NOX/ROS pathways; causes crystal nephropathy, kidney stones, urolithiasis, and acute kidney injury.
[2]
Nitrogen dopant in single-step synthesis of doped biochars
Enhances adsorptive properties of carbon materials for dye removal
[1]
Fraudulent adulterant in milk and dairy products (added to artificially inflate apparent protein content); by-product of cyromazine (a veterinary medicine); migrates from packaging materials; enters food chain via contaminated water/soil or animal feed.
[2]
Classification by use
Doping agents in material synthesis
Reagents for modifying carbon-based adsorbents
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[Cite:1] Synthesis, Characterization, and Adsorption Properties of Nitrogen-Doped Nanoporous Biochar: Efficient Removal of Reactive Orange 16 Dye and Colorful Effluents, Nanomaterials, 2023, 13(14), 2045
[Cite:2] Melamine and Cyanuric Acid in Milk and Their Quantities, Analytical Methods and Exposure Risk: A Systematic Review and Meta-analysis, Journal of Food Protection, Volume 88, Issue 3, 26 February 2025, 100454