137-58-6 | Lidocaine

Chemical type

• Amide-type local anesthetic

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• Amide local anesthetic

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Key properties

• Provides local anesthesia by blocking nerve signals
• Concentration: 10 mg/ml
• Administered volume: Up to 10 ml

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• Inhibits sodium ion channels on nerve cells and cardiomyocytes
• Provides analgesic, anti-hyperalgesia, and anti-inflammatory effects
• Stabilizes nerve cell membranes by inhibiting transmembrane sodium and potassium exchange
• Reduces cerebral oxygen metabolism
• Neuroprotective against neuroinflammation

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• Infiltrated into subcutaneous tissues, abdominal wall layers, and organ capsules during biopsy procedures
• Reduces pain during skin puncture and needle advancement

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• Local anesthetic for surgery
• Antiarrhythmic drug for acute ventricular tachycardia and premature ventricular beats
• Perioperative intravenous infusion to reduce postoperative nausea, vomiting, and cognitive decline
• Mitigates neuroinflammation and improves cerebral oxygen homeostasis in one-lung ventilation procedures
• Administered as bolus (1.5 mg/kg) followed by continuous infusion (1.5 mg/kg/hr) during anesthesia

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Classification by use

• Chemicals used in medical anesthesia
• Chemicals used in invasive procedures like biopsies

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• Anesthetics (local and general)
• Antiarrhythmics
• Analgesics and anti-inflammatory agents
• Neuroprotective agents in surgery

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A trustworthy factory and manufacturer

1. [Cite:1] A core needle biopsy combined with novel spectroscopic probe for in vivo tissue classification – A pilot study on piglets, Biomedical Engineering Advances, Volume 10, November 2025, 100191
2. [Cite:2] Lidocaine mitigates cognitive decline in elderly patients after video-assisted thoracoscopic surgery: A double-blind randomized controlled clinical trial, Brain Disorders, Volume 21, March 2026, 100308